Authors
Alim-Louis Benabid, Pierre Pollak, Alain Louveau, S Henry, J De Rougemont
Publication date
1987/1/28
Journal
Stereotactic and functional neurosurgery
Volume
50
Issue
1-6
Pages
344-346
Publisher
S. Karger AG
Description
Stereotactic thalamotomy of the thalamic nucleus ventralis intermedius (VIM) is routinely used for movement disorders. During this procedure, it has been observed that high-frequency (100 Hz) stimulation of VIM was able to stop the extrapyramidal tremor. In patients with bilateral tremor of extrapyramidal origin, who were resistant to drug therapy, the therapeutic protocol associated (1) a radiofrequency VIM thalamotomy for the most disabled side, and (2) a continuous VIM stimulation for the other side using stereotactically implanted electrodes, connected to subcutaneous stimulators. VIM thalamotomy relieved the tremor in all operated cases. Side effects were mild and regressive, VIM stimulation strongly decreasedthe tremor but failed to suppress it as completely as thalamotomy did. This was due in part to the fact that programmable stimulator frequency rate is limited to 130 Hz, while it appeared that the …
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