Authors
Qiuchang Sun, Yinsheng Chen, Chaofeng Liang, Yuanshen Zhao, Xiaofei Lv, Yan Zou, Kai Yan, Hairong Zheng, Dong Liang, Zhi-Cheng Li
Publication date
2021/12
Journal
Radiology
Volume
301
Issue
3
Pages
654-663
Publisher
Radiological Society of North America
Description
Background
The biologic meaning of prognostic radiomics phenotypes remains poorly understood, hampered in part by lack of multicenter reproducible evidence.
Purpose
To uncover the biologic meaning of individual prognostic radiomics phenotypes in glioblastomas using paired MRI and RNA sequencing data and to validate the reproducibility of the identified radiogenomics linkages externally.
Materials and Methods
This retrospective multicenter study included four data sets gathered between January 2015 and December 2016. From a radiomics analysis set, a 13-feature radiomics signature was built using preoperative MRI for overall survival …
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Scholar articles
Q Sun, Y Chen, C Liang, Y Zhao, X Lv, Y Zou, K Yan… - Radiology, 2021