Authors
Marie-Jeanne Mayaux, Marianne Burgard, Jean-Paul Teglas, Jacqueline Cottalorda, Anne Krivine, François Simon, Jacqueline Puel, Catherine Tamalet, Dominique Dormont, Bernard Masquelier, Anne Doussin, Christine Rouzioux, Stéphane Blanche, B Pautard, D Brault, J Mamou, A Broyart, M Dandine, X Hernandorena, P Balde, E Lachassine, D Douard, H Fleury, B Masquelier, I Gilles, A Gantzer, AM Colin-Gorki, J Brouard, F Freymuth, L Keros, P Labrune, M Vial, F Mazy, C Floch, P Bourdon, M Duval-Arnould, C Huraux-Rendu, S Lemerle, M Boddaert, MF Denavit, K Lahsinat, C Pascal, A Leblanc, A May, C Dallot, D Dormont, B Bader-Meunier, E Dussaix, M Tardieu, H Seaume, P Wipff, P Deboisse, G Michel, C Tamalet, D Vallée, C Crumière, A Saillant, B Le Lorier, C Botto, D Seguy, P Talon, C Huret, J Nicolas, J Lalande, F Mechineau-Lacroix, D Berterottière, J Cottalorda, A Deville, F Monpoux, A de Crepy, F Simon, S Parat, G Firtion, M Ronzier, C Brunner, N Ciraru-Vigneron, B Heller-Roussin, S Blanche, M Burgard, D Girault, C Rouzioux, J Terris, F Veber, JM Huraux, G Noseda, M Levine, E Vilmer, A Vallet, L Marpeau, F Parnet Mathieu, C Aufrant, C Francoual, A Krivine, F Hervé, C Courpotin, C Dollfus, C Carlus Moncomble, MC Rousset, G Mouchnino, V Brossard, C Buffet-Janvresse, M Robin, F Labbe-Filou, MC Allemon, J-M Retbi, P Narcy, A-M Raison Boulley, J Puel, J Tricoire, F Barin, J-C Borderon, R Busuttil, A Vinas, F Guillot, A Lacroix-Coutry
Publication date
1996/2/28
Journal
Jama
Volume
275
Issue
8
Pages
606-610
Publisher
American Medical Association
Description
Objective
—To identify clinical and laboratory parameters at birth that are associated with the rapidly progressive form of human immunodeficiency virus type 1 (HIV-1) disease in children born to infected mothers.
Design
—Multicenter, prospective study of infants born to HIV-seropositive mothers.
Setting
—A total of 62 obstetric and pediatric centers in France.
Participants
—Of 1386 children born to HIV-1—seropositive mothers at least 18 months before the cutoff date, 267 were infected. Infection was defined as serological positivity at 18 months or death from HIV disease before this age.
Main Outcome Measure
—Category C events (including opportunistic infections, recurrent severe bacterial infections, cancers, specific encephalopathy, and wasting syndrome) in the new pediatric Centers for Disease Control and Prevention classification during the first year of life, according to clinical, immunological, and virological …
Total citations
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