Authors
David Granton, Myanca Rodrigues, Valeria Raparelli, Kimia Honarmand, Arnav Agarwal, Jan O Friedrich, Benedetta Perna, Riccardo Spaggiari, Valeria Fortunato, Gianluca Risdonne, Michelle Kho, Sandra VanderKaay, Dipayan Chaudhuri, Carolina Gomez-Builes, Frédérick D'Aragon, Daniel Wiseman, Vincent Issac Lau, Celina Lin, Julie Reid, Vatsal Trivedi, Varuna Prakash, Emilie Belley-Cote, Maha Al Mandhari, Lehana Thabane, Louise Pilote, Karen EA Burns
Publication date
2024/5/1
Source
BMJ open
Volume
14
Issue
5
Pages
e081118
Publisher
British Medical Journal Publishing Group
Description
Objective
To characterise sex and gender-based analysis (SGBA) and diversity metric reporting, representation of female/women participants in acute care trials and temporal changes in reporting before and after publication of the 2016 Sex and Gender Equity in Research guideline.
Design
Systematic review.
Data sources
We searched MEDLINE for trials published in five leading medical journals in 2014, 2018 and 2020.
Study selection
Trials that enrolled acutely ill adults, compared two or more interventions and reported at least one clinical outcome.
Data abstraction and synthesis
4 reviewers screened citations and 22 reviewers abstracted data, in duplicate. We compared reporting differences between intensive care unit (ICU) and cardiology trials.
Results
We included 88 trials (75 (85.2%) ICU and 13 (14.8%) cardiology) (n=111 428; 38 140 (34.2%) females/women). Of 23 (26.1%) trials that reported an SGBA …
Scholar articles
D Granton, M Rodrigues, V Raparelli, K Honarmand… - BMJ open, 2024