Authors
Jacqueline Fitzgerald, Katherine Johnson, Elizabeth Kehoe, Arun LW Bokde, Hugh Garavan, Louise Gallagher, Jane McGrath
Publication date
2015/4
Journal
Autism Research
Volume
8
Issue
2
Pages
136-152
Description
Background
Attention orienting is a cognitive process that facilitates the movement of attention focus from one location to another: this may be impaired in autism spectrum disorder (ASD). Dorsal and ventral attention networks (DAN and VAN) sub‐serve the process of attention orienting. This study investigated the functional connectivity of attention orienting in these networks in ASD using the Posner Cueing Task.
Method
Twenty‐one adolescents with ASD and 21 age and IQ matched controls underwent functional magnetic resonance imaging. A psychophysical interaction (PPI) analysis was implemented to investigate task‐dependent functional connectivity, measuring synchronicity of brain regions during the task. Regions of interest (ROI) were selected to explore functional connectivity in the DAN during cue‐only conditions and in the VAN during invalid and valid trials.
Results
Behaviourally, the ASD and …
Total citations
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