Authors
Marcel Leist, Marja Jäättelä
Publication date
2001/8
Source
Nature reviews Molecular cell biology
Volume
2
Issue
8
Pages
589-598
Publisher
Nature Publishing Group UK
Description
A single family of proteases, the caspases, has long been considered the pivotal executioner of all programmed cell death. However, recent findings of evolutionarily conserved, caspase-independent controlled death mechanisms have opened new perspectives on the biology of cell demise, with particular implications for neurobiology, cancer research and immunological processes.
Total citations
Scholar articles
M Leist, M Jäättelä - Nature reviews Molecular cell biology, 2001