Authors
Jing Yang, Parker Antin, Geert Berx, Cédric Blanpain, Thomas Brabletz, Marianne Bronner, Kyra Campbell, Amparo Cano, Jordi Casanova, Gerhard Christofori, Shoukat Dedhar, Rik Derynck, Heide L Ford, Jonas Fuxe, Antonio García de Herreros, Gregory J Goodall, Anna-Katerina Hadjantonakis, Ruby YJ Huang, Chaya Kalcheim, Raghu Kalluri, Yibin Kang, Yeesim Khew-Goodall, Herbert Levine, Jinsong Liu, Gregory D Longmore, Sendurai A Mani, Joan Massagué, Roberto Mayor, David McClay, Keith E Mostov, Donald F Newgreen, M Angela Nieto, Alain Puisieux, Raymond Runyan, Pierre Savagner, Ben Stanger, Marc P Stemmler, Yoshiko Takahashi, Masatoshi Takeichi, Eric Theveneau, Jean Paul Thiery, Erik W Thompson, Robert A Weinberg, Elizabeth D Williams, Jianhua Xing, Binhua P Zhou, Guojun Sheng, EMT International Association (TEMTIA)
Publication date
2020/6/10
Source
Nature reviews Molecular cell biology
Volume
21
Issue
6
Pages
341-352
Publisher
Nature Publishing Group UK
Description
Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migration and invasion. EMT occurs in a diverse range of physiological and pathological conditions and is driven by a conserved set of inducing signals, transcriptional regulators and downstream effectors. With over 5,700 publications indexed by Web of Science in 2019 alone, research on EMT is expanding rapidly. This growing interest warrants the need for a consensus among researchers when referring to and undertaking research on EMT. This Consensus Statement, mediated by ‘the EMT International Association’ (TEMTIA), is the outcome of a 2-year-long discussion among EMT researchers and aims to both clarify the nomenclature and provide definitions and guidelines for EMT research in future publications. We trust that …
Scholar articles
J Yang, P Antin, G Berx, C Blanpain, T Brabletz… - Nature reviews Molecular cell biology, 2020