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Background. It has been speculated that increased levels of circulating or intraperitoneal pro‐inflammatory cytokines such as interleukin 6, and pro‐angiogenic vascular endothelial growth factor (VEGF) may contribute to high peritoneal small‐solute transport rate (PSTR) in continuous ambulatory peritoneal dialysis (CAPD) patients. In this study we evaluated possible relationships between plasma and dialysate IL‐6 and VEGF levels and PSTR.

Methods. Forty CAPD patients (mean age±SD of 58±14 years) with no apparent inflammation process or disease, who had been on CAPD for 19±15 months (range 3–56 months) were included in the study. Peritoneal equilibration test (PET) was used to evaluate PSTR. Patients were divided into two groups: high‐average and high transporters (H/A; D/P_creat≥0.65) and low‐average and low transporters (L/A; D/P_creat<0.64). Albumin and IgG …