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We investigate the problem of optimal request routing and content caching in a heterogeneous network supporting in-network content caching with the goal of minimizing average content access delay. Here, content can either be accessed directly from a back-end server (where content resides permanently) or be obtained from one of multiple in-network caches. To access a piece of content, a user must decide whether to route its request to a cache or to the back-end server. Additionally, caches must decide which content to cache. We investigate the problem complexity of two problem formulations, where the direct path to the back-end server is modeled as i) a congestion-sensitive or ii) a congestion-insensitive path, reflecting whether or not the delay of the uncached path to the back-end server depends on the user request load, respectively. We show that the problem is NP-complete in both cases. We prove that …