Authors
Catherine Lord, Eva Petkova, Vanessa Hus, Weijin Gan, Feihan Lu, Donna M Martin, Opal Ousley, Lisa Guy, Raphael Bernier, Jennifer Gerdts, Molly Algermissen, Agnes Whitaker, James S Sutcliffe, Zachary Warren, Ami Klin, Celine Saulnier, Ellen Hanson, Rachel Hundley, Judith Piggot, Eric Fombonne, Mandy Steiman, Judith Miles, Stephen M Kanne, Robin P Goin-Kochel, Sarika U Peters, Edwin H Cook, Stephen Guter, Jennifer Tjernagel, Lee Anne Green-Snyder, Somer Bishop, Amy Esler, Katherine Gotham, Rhiannon Luyster, Fiona Miller, Jennifer Olson, Jennifer Richler, Susan Risi
Publication date
2012/3/5
Journal
Archives of general psychiatry
Volume
69
Issue
3
Pages
306-313
Publisher
American Medical Association
Description
Context
Best-estimate clinical diagnoses of specific autism spectrum disorders (autistic disorder, pervasive developmental disorder–not otherwise specified, and Asperger syndrome) have been used as the diagnostic gold standard, even when information from standardized instruments is available.
Objective
To determine whether the relationships between behavioral phenotypes and clinical diagnoses of different autism spectrum disorders vary across 12 university-based sites.
Design
Multisite observational study collecting clinical phenotype data (diagnostic, developmental, and demographic) for genetic research. Classification trees were used to identify characteristics that predicted diagnosis across and within sites.
Setting
Participants were recruited through 12 university-based autism service providers into a genetic study of autism.
Participants
A total of 2102 probands (1814 male probands) between 4 and 18 …
Total citations
Scholar articles
C Lord, E Petkova, V Hus, W Gan, F Lu, DM Martin… - Archives of general psychiatry, 2012