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In order to evaluate the seismic risk of transportation networks, it is necessary to develop a methodology that integrates the probabilities of occurrence of seismic events in a region, the vulnerability of the civil infrastructure, and the consequences of the seismic hazard to the society, environment, and economy. In this article, a framework for the time-variant seismic sustainability and risk assessment of highway bridge networks is presented. The sustainability of the network is quantified in terms of its social, environmental, and economic metrics. These include the expected downtime, expected energy waste and carbon dioxide emissions, and the expected loss. The methodology considers the probability of occurrence of a set of seismic scenarios that reflect the seismic activity of the region. The performance of network links is quantified based on individual bridge performance evaluated through fragility analyses. The …