Authors
Steven F Petit, Binbin Wu, Michael Kazhdan, André Dekker, Patricio Simari, Rachit Kumar, Russel Taylor, Joseph M Herman, Todd McNutt
Publication date
2012/1/1
Journal
Radiotherapy and Oncology
Volume
102
Issue
1
Pages
38-44
Publisher
Elsevier
Description
PURPOSE
To develop a model to assess the quality of an IMRT treatment plan using data of prior patients with pancreatic adenocarcinoma.
METHODS
The dose to an organ at risk (OAR) depends in large part on its orientation and distance to the planning target volume (PTV). A database of 33 previously treated patients with pancreatic cancer was queried to find patients with less favorable PTV-OAR configuration than a new case. The minimal achieved dose among the selected patients should also be achievable for the OAR of the new case. This way the achievable doses to the OARs of 25 randomly selected pancreas cancer patients were predicted. The patients were replanned to verify if the predicted dose could be achieved. The new plans were compared to their original clinical plans.
RESULTS
The predicted doses were achieved within 1 and 2Gy for more than 82% and 94% of the patients, respectively …
Scholar articles
SF Petit, B Wu, M Kazhdan, A Dekker, P Simari… - Radiotherapy and Oncology, 2012