Authors
JA Obeso, Maria Stamelou, CG Goetz, Werner Poewe, AE Lang, D Weintraub, David Burn, Glenda Margaret Halliday, E Bezard, SJMD Przedborski, Stephane Lehericy, DJ Brooks, JC Rothwell, M Hallett, MR DeLong, Connie Marras, CM Tanner, GW Ross, J William Langston, Christoph Klein, Vincenzo Bonifati, Joseph Jankovic, AM Lozano, Günther Deuschl, H Bergman, E Tolosa, M Rodriguez‐Violante, S Fahn, RB Postuma, Daniela Berg, K Marek, DG Standaert, DJ Surmeier, CW Olanow, JH Kordower, P Calabresi, Anthony Henry Vernon Schapira, AJ Stoessl
Publication date
2017/9
Source
Movement disorders
Volume
32
Issue
9
Pages
1264-1310
Description
This article reviews and summarizes 200 years of Parkinson's disease. It comprises a relevant history of Dr. James Parkinson's himself and what he described accurately and what he missed from today's perspective. Parkinson's disease today is understood as a multietiological condition with uncertain etiopathogenesis. Many advances have occurred regarding pathophysiology and symptomatic treatments, but critically important issues are still pending resolution. Among the latter, the need to modify disease progression is undoubtedly a priority. In sum, this multiple‐author article, prepared to commemorate the bicentenary of the shaking palsy, provides a historical state‐of‐the‐art account of what has been achieved, the current situation, and how to progress toward resolving Parkinson's disease. © 2017 International Parkinson and Movement Disorder Society
Scholar articles
JA Obeso, M Stamelou, CG Goetz, W Poewe, AE Lang… - Movement disorders, 2017