Authors
Anthony De Soyza, Amanda J Hall, Eshwar Mahenthiralingam, Pavel Drevinek, Wieslaw Kaca, Zuzanna Drulis‐Kawa, Stoyanka R Stoitsova, Veronika Toth, Tom Coenye, James EA Zlosnik, Jane L Burns, Isabel Sá‐Correia, Daniel De Vos, Jean‐Paul Pirnay, Timothy J. Kidd, David Reid, Jim Manos, Jens Klockgether, Lutz Wiehlmann, Burkhard Tümmler, Siobhán McClean, Craig Winstanley, EU FP7 funded COST Action BM1003 “Cell surface virulence determinants of cystic fibrosis pathogens”
Publication date
2013/12
Journal
Microbiologyopen
Volume
2
Issue
6
Pages
1010-1023
Description
Pseudomonas aeruginosa is a major opportunistic pathogen in cystic fibrosis (CF) patients and causes a wide range of infections among other susceptible populations. Its inherent resistance to many antimicrobials also makes it difficult to treat infections with this pathogen. Recent evidence has highlighted the diversity of this species, yet despite this, the majority of studies on virulence and pathogenesis focus on a small number of strains. There is a pressing need for a P. aeruginosa reference panel to harmonize and coordinate the collective efforts of the P. aeruginosa research community. We have collated a panel of 43 P. aeruginosa strains that reflects the organism's diversity. In addition to the commonly studied clones, this panel includes transmissible strains, sequential CF isolates, strains with specific virulence characteristics, and strains that represent serotype, genotype or geographic diversity. This focussed …
Scholar articles
A De Soyza, AJ Hall, E Mahenthiralingam, P Drevinek… - Microbiologyopen, 2013