Authors
Hong-Qi Fan, Yan Li, Lutgarde Thijs, Tine W Hansen, Jose Boggia, Masahiro Kikuya, Kristina Björklund-Bodegård, Tom Richart, Takayoshi Ohkubo, Jørgen Jeppesen, Christian Torp-Pedersen, Eamon Dolan, Tatiana Kuznetsova, Katarzyna Stolarz-Skrzypek, Valerie Tikhonoff, Sofia Malyutina, Edoardo Casiglia, Yuri Nikitin, Lars Lind, Edgardo Sandoya, Kalina Kawecka-Jaszcz, Yutaka Imai, Hans Ibsen, Eoin O'Brien, Jiguang Wang, Jan A Staessen, International Database on Ambulatory blood pressure in relation to Cardiovascular Outcomes (IDACO) Investigators
Publication date
2010/10/1
Journal
Journal of hypertension
Volume
28
Issue
10
Pages
2036-2045
Publisher
LWW
Description
Background
We and other investigators previously reported that isolated nocturnal hypertension on ambulatory measurement (INH) clustered with cardiovascular risk factors and was associated with intermediate target organ damage. We investigated whether INH might also predict hard cardiovascular endpoints.
Methods and results
We monitored blood pressure (BP) throughout the day and followed health outcomes in 8711 individuals randomly recruited from 10 populations (mean age 54.8 years, 47.0% women). Of these, 577 untreated individuals had INH (daytime BP< 135/85 mmHg and night-time BP≥ 120/70 mmHg) and 994 untreated individuals had isolated daytime hypertension on ambulatory measurement (IDH; daytime BP≥ 135/85 mmHg and night-time BP< 120/70 mmHg). During follow-up (median 10.7 years), 1284 deaths (501 cardiovascular) occurred and 1109 participants experienced a fatal or …
Total citations
Scholar articles
HQ Fan, Y Li, L Thijs, TW Hansen, J Boggia, M Kikuya… - Journal of hypertension, 2010