Authors
Wen-Yi Yang, Jesus D Melgarejo, Lutgarde Thijs, Zhen-Yu Zhang, José Boggia, Fang-Fei Wei, Tine W Hansen, Kei Asayama, Takayoshi Ohkubo, Jørgen Jeppesen, Eamon Dolan, Katarzyna Stolarz-Skrzypek, Sofia Malyutina, Edoardo Casiglia, Lars Lind, Jan Filipovský, Gladys E Maestre, Yan Li, Ji-Guang Wang, Yutaka Imai, Kalina Kawecka-Jaszcz, Edgardo Sandoya, Krzysztof Narkiewicz, Eoin O’Brien, Peter Verhamme, Jan A Staessen, International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcomes (IDACO) Investigators
Publication date
2019/8/6
Journal
Jama
Volume
322
Issue
5
Pages
409-420
Publisher
American Medical Association
Description
Importance
Blood pressure (BP) is a known risk factor for overall mortality and cardiovascular (CV)-specific fatal and nonfatal outcomes. It is uncertain which BP index is most strongly associated with these outcomes.
Objective
To evaluate the association of BP indexes with death and a composite CV event.
Design, Setting, and Participants
Longitudinal population-based cohort study of 11 135 adults from Europe, Asia, and South America with baseline observations collected from May 1988 to May 2010 (last follow-ups, August 2006-October 2016).
Exposures
Blood pressure measured by an observer or an automated office machine; measured for 24 hours, during the day or the night; and the dipping ratio (nighttime divided by daytime readings).
Main Outcomes and Measures
Multivariable-adjusted hazard ratios (HRs) expressed the risk of death or a CV event associated with BP increments of 20/10 mm Hg …
Scholar articles
WY Yang, JD Melgarejo, L Thijs, ZY Zhang, J Boggia… - Jama, 2019