Authors
Mitchell R Goldsworthy, Brenton Hordacre
Publication date
2017/6/6
Journal
The Journal of physiology
Volume
595
Issue
11
Pages
3265
Publisher
Wiley
Description
There has been a rapid growth in the use of non-invasive brain stimulation to induce neuroplasticity and modulate human brain function over the past decade. An example of this is transcranial direct current stimulation (tDCS), which involves the application of weak electrical currents between at least two electrodes placed over the scalp. When applied to the primary motor cortex (M1), tDCS can induce lasting polarity-dependent changes in excitability, with facilitation following anodal stimulation and suppression following cathodal stimulation. These changes share similarities with the long-term potentiation(LTP) and long-term depression (LTD) observed in animal models, and importantly, there is some evidence that tDCS can have positive therapeutic effects for patients with various neurological and psychiatric conditions. Of the various techniques developed for non-invasively inducing neuroplasticity in the human …
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