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Non-pharmaceutical interventions (NPIs) and societal behavioural changes during the COVID-19 pandemic altered not only the spread of SARS-CoV-2, but also the predictable seasonal circulation patterns of many endemic viral illnesses in children. 1 Before 2020, respiratory syncytial virus (RSV) and non-pandemic influenza viruses peaked in the winter in northern and southern hemispheres outside of tropical areas. 2 In temperate climates, non-polio enteroviruses circulated in the summer to autumn3 in cyclical patterns. 4 The COVID-19 pandemic has led to a departure from these patterns and, in many locations, usual circulation of these viruses was absent for more than a year only to resurge in unexpected ways. Past and present pandemic disruptions make it essential to prepare for further uncertainty in future endemic virus circulation among children. After the relaxation of the major NPI measures in many …