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The escalating prevalence of elevated Body Mass Index (BMI) levels worldwide has led to a substantial burden on healthcare systems, posing considerable economic challenges. This research paper presents a comparative cost assessment that delves into the intricate relationship between BMI and its financial impact on health ser-vices. The rise in obesity and overweight individuals has been linked to a surge in chronic health conditions, including cardiovascular diseases, type 2 diabetes, muscu-loskeletal disorders, and certain cancers, which necessitate extensive medical inter-ventions, long-term treatments, and management, thereby amplifying healthcare expenditures significantly. Beyond direct healthcare costs, the economic repercus-sions encompass productivity losses, absenteeism from work, and diminished quality of life for affected individuals. This comparative cost assessment aims to analyze healthcare expenditure data from various demographic groups to uncover the dif-ferential impact of BMI on healthcare costs. By exploring preventive measures, in-terventions, and policy frameworks, the study seeks to mitigate the economic strain on healthcare systems resulting from BMI-related health complications. Under-standing the intricate relationship between BMI and healthcare costs is crucial in formulating evidence-based strategies to address this growing challenge, providing valuable insights for policymakers, healthcare practitioners, and stakeholders, guid-ing the implementation of effective measures to alleviate the financial burden on health services while promoting improved health outcomes for populations globally.