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A physical unclonable function (PUF), like a fingerprint, exploits manufacturing randomness to endow each physical item with a unique identifier. One primary PUF application is the secure derivation of volatile cryptographic keys using a fuzzy extractor (FE) comprising: 1) a secure sketch and 2) an entropy extractor. Although the entropy extractor can be lightweight, the overhead of the secure sketch responsible for correcting naturally noisy PUF responses is usually high. We observe that, in general, response unreliability with respect to an enrolled reference measurement increases with increasing differences between the in-the-field PUF operating condition and the operating condition used in evaluating the enrolled reference response. For the first time, we exploit such an inadvertent but important observation. In contrast to the conventional single reference response enrollment, we propose enrolling multiple …