Authors
G Sꎬ Patel, K Jain, R Kumar, AH Strickland, L Pellegrini, John Slavotinek, Michael Eaton, William McLeay, Timothy Price, M Ly, Shahid Ullah, Bogda Koczwara, Ganessan Kichenadasse, CS Karapetis
Publication date
2014/1
Journal
Supportive care in cancer
Volume
22
Pages
121-128
Publisher
Springer Berlin Heidelberg
Description
Purpose
Indwelling central venous catheters (CVCs) have been increasingly used to enable delivery of intravenous chemotherapy. We aimed to compare the safety and cost of two commonly used CVCs, peripherally inserted central venous catheter (PICCs) and ports, in the delivery of chemotherapy in patients with non-haematological malignancies.
Methods
Seventy patients were randomly assigned to receive either a PICC or a port. The primary endpoint was occurrence of major complications, which required removal of the CVC and secondary endpoints included occurrence of any complications.
Results
Port devices were associated with fewer complications compared with PICC lines (hazard ratio of 0.25, CI, 0.09–0.86, P = 0.038). Major complication rate was lower in the port arm compared to the PICC arm (0.047 …
Total citations
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