Authors
Wasim Jafri, Javed Yakoob, Shahab Abid, S Siddiqui, Safia Awan, SQ Nizami
Publication date
2010/2
Journal
Acta Paediatrica
Volume
99
Issue
2
Pages
279-282
Publisher
Blackwell Publishing Ltd
Description
Aim:  We estimated the prevalence, age of acquisition and risk factors for Helicobacter pylori (H. pylori) seroprevalence in children aged 1–15 years.
Methods:  Exposure was assessed using ELISA. Parents responded to a questionnaire regarding number of individuals sharing house, rooms, water source, latrines, housing and assessment of socioeconomic status (SES) by Hollingshead Index.
Results:  Serum of 1976 children was tested. Helicobacter pylori seropositivity in children aged 11–15 years was 53.5% (OR: 2.0, 95% CI: 1.58–2.5). It increased with moderate crowding index (CRI) of 2–4 to 45.9% (OR: 1.23, 95% CI: 0.92–1.63) and to 51.2% with CRI >4 (OR: 1.52, 95% CI: 1.12–2.06). In middle SES, seropositivity was 50.5% (331/655) (OR: 1.7, 95% CI: 1.29–2.35), whereas in lower SES, it was 47.1% (500/1062) (OR: 1.5, 95% CI: 1.1–2.0). Multivariate analysis showed that Helicobacter pylori …
Total citations
20092010201120122013201420152016201720182019202020212022202320241410810976111011107261