Authors
AD Dinsmore, DT Wong, Philip Nelson, AG Yodh
Publication date
1998/1/12
Journal
Physical Review Letters
Volume
80
Issue
2
Pages
409
Publisher
American Physical Society
Description
We explore the interplay of membrane curvature and nonspecific binding due to excluded-volume effects among colloidal particles inside lipid bilayer vesicles. We trapped submicron spheres of two different sizes inside a pear-shaped, multilamellar vesicle and found the larger spheres to be pinned to the vesicle's surface and pushed in the direction of increasing curvature. A simple model predicts that hard spheres can induce shape changes in flexible vesicles. The results demonstrate an important relationship between the shape of a vesicle or pore and the arrangement of particles within it.
Total citations
Scholar articles
AD Dinsmore, DT Wong, P Nelson, AG Yodh - Physical Review Letters, 1998