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Substantial research has shown that positive psychological interventions (PPIs) have beneficial effects on well-being. This article evaluates whether PPIs would be effective for everyone, across different cultures. It starts by reviewing the effectiveness of PPIs among the general population, as well as their effectiveness in ameliorating depressive symptoms and increasing well-being among clinical samples. Though generally beneficial, PPIs however, may not be equally effective across cultures. We present evidence showing that certain types of PPIs may be less effective for Asians than those from Western cultures. Next, the article examines whether prosocial behavior may be a PPI that is universally beneficial and the possible explanations for its widespread benefits. Finally, we proceed to propose how the current repertoire of PPIs may be expanded to include new types that may be more suited for those in …