Authors
Joshua Z Goldenberg, Andrew Day, Grant D Brinkworth, Junko Sato, Satoru Yamada, Tommy Jönsson, Jennifer Beardsley, Jeffrey A Johnson, Lehana Thabane, Bradley C Johnston
Publication date
2021/1
Source
BMJ
Volume
372
Publisher
British Medical Journal Publishing Group
Description
Objective
To determine the efficacy and safety of low carbohydrate diets (LCDs) and very low carbohydrate diets (VLCDs) for people with type 2 diabetes.
Design
Systematic review and meta-analysis.
Data sources
Searches of CENTRAL, Medline, Embase, CINAHL, CAB, and grey literature sources from inception to 25 August 2020.
Study selection
Randomized clinical trials evaluating LCDs (<130 g/day or <26% of a 2000 kcal/day diet) and VLCDs (<10% calories from carbohydrates) for at least 12 weeks in adults with type 2 diabetes were eligible.
Data extraction
Primary outcomes were remission of diabetes (HbA1c <6.5% or fasting glucose <7.0 mmol/L, with or without the use of diabetes medication), weight loss, HbA1c, fasting glucose, and adverse events. Secondary outcomes included health related quality of life and biochemical laboratory data. All articles and outcomes were independently screened …
Total citations
202020212022202320241568310862