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Rotations are important practices for managing soil fertility on smallholder farms. Six cropping sequences (cassava, pigeonpea, mucuna–maize–mucuna, cowpea–maize–cowpea, maize–maize–maize, and speargrass fallow) were evaluated during 2003–2004 in Wenchi district of Ghana for their effects on the profitability of the different rotations and the productivity of subsequent maize. Soil chemical properties were not significantly affected by cropping sequence. On the researcher-managed and farmer-managed plots maize grain yields were significantly influenced by cropping sequence. On the researcher-managed plots maize grain yield ranged from 1.0tha⁻¹ after speargrass fallow to 3.0tha⁻¹ with cassava cropping when N fertiliser was not applied to maize and from 2.1tha⁻¹ with continuous maize to 4.2tha⁻¹ with mucuna–maize–mucuna when 60kgNha⁻¹ was applied to maize. On the farmer-managed …