Authors
Yvonne M Badke, Ronald O Bates, Catherine W Ernst, Clint Schwab, Juan P Steibel
Publication date
2012/12
Journal
BMC genomics
Volume
13
Pages
1-10
Publisher
BioMed Central
Description
Background
The success of marker assisted selection depends on the amount of linkage disequilibrium (LD) across the genome. To implement marker assisted selection in the swine breeding industry, information about extent and degree of LD is essential. The objective of this study is to estimate LD in four US breeds of pigs (Duroc, Hampshire, Landrace, and Yorkshire) and subsequently calculate persistence of phase among them using a 60 k SNP panel. In addition, we report LD when using only a fraction of the available markers, to estimate persistence of LD over distance.
Results
Average r 2 between adjacent SNP across all chromosomes was 0.36 for Landrace, 0.39 for Yorkshire, 0.44 for Hampshire and 0.46 for Duroc. For markers 1 Mb apart, r 2 ranged from 0.15 for Landrace to 0.20 for Hampshire …
Total citations
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Scholar articles
YM Badke, RO Bates, CW Ernst, C Schwab, JP Steibel - BMC genomics, 2012