Authors
Joan K Lunney, Juan Pedro Steibel, James M Reecy, Eric Fritz, Max F Rothschild, Maureen Kerrigan, Benjamin Trible, Raymond RR Rowland
Publication date
2011/12
Source
BMC proceedings
Volume
5
Pages
1-5
Publisher
BioMed Central
Description
Background
Understanding the role of host genetics in resistance to porcine reproductive and respiratory syndrome virus (PRRSV) infection, and the effects of PRRS on pig health and related growth, are goals of the PRRS Host Genetics Consortium (PHGC).
Methods
The project uses a nursery pig model to assess pig resistance/susceptibility to primary PRRSV infection. To date, 6 groups of 200 crossbred pigs from high health farms were donated by commercial sources. After acclimation, the pigs were infected with PRRSV in a biosecure facility and followed for 42 days post infection (dpi). Blood samples were collected at 0, 4, 7, 10, 14, 21, 28, 35 and 42 dpi for serum and whole blood RNA gene expression analyses; weekly weights were recorded for growth traits. All data have been entered into the PHGC relational database. Genomic DNAs from all …
Scholar articles
JK Lunney, JP Steibel, JM Reecy, E Fritz… - BMC proceedings, 2011