Authors
Eli Puterman, Alison Gemmill, Deborah Karasek, David Weir, Nancy E Adler, Aric A Prather, Elissa S Epel
Publication date
2016/10/18
Journal
Proceedings of the National Academy of Sciences
Volume
113
Issue
42
Pages
E6335-E6342
Publisher
National Academy of Sciences
Description
Stress over the lifespan is thought to promote accelerated aging and early disease. Telomere length is a marker of cell aging that appears to be one mediator of this relationship. Telomere length is associated with early adversity and with chronic stressors in adulthood in many studies. Although cumulative lifespan adversity should have bigger impacts than single events, it is also possible that adversity in childhood has larger effects on later life health than adult stressors, as suggested by models of biological embedding in early life. No studies have examined the individual vs. cumulative effects of childhood and adulthood adversities on adult telomere length. Here, we examined the relationship between cumulative childhood and adulthood adversity, adding up a range of severe financial, traumatic, and social exposures, as well as comparing them to each other, in relation to salivary telomere length. We examined …
Total citations
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Scholar articles
E Puterman, A Gemmill, D Karasek, D Weir, NE Adler… - Proceedings of the National Academy of Sciences, 2016