Authors
Lonnie K Zeltzer, Qian Lu, Wendy Leisenring, Jennie CI Tsao, Christopher Recklitis, Gregory Armstrong, Ann C Mertens, Leslie L Robison, Kirsten K Ness
Publication date
2008/2/1
Journal
Cancer Epidemiology Biomarkers & Prevention
Volume
17
Issue
2
Pages
435-446
Publisher
American Association for Cancer Research
Description
Purpose: Psychological outcomes, health-related quality of life (HRQOL), and life satisfaction are compared between 7,147 adult childhood cancer survivors and 388 siblings from the Childhood Cancer Survivor Study, examining demographic and diagnosis/treatment outcome predictors.
Methods: Psychological distress, HRQOL, and life satisfaction were measured by the Brief Symptom Inventory-18, the Medical Outcomes Survey Short Form-36, and Cantril Ladder of Life, respectively. A self-report questionnaire provided demographic/health information and medical record abstraction provided cancer/treatment data. Siblings' and survivors' scores were compared using generalized linear mixed models, and predictor effects of demographic and cancer/treatment variables were analyzed by multivariate logistic regression.
Results: Although survivors report greater symptoms of global distress (mean, 49.17 …
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Scholar articles
LK Zeltzer, Q Lu, W Leisenring, JCI Tsao, C Recklitis… - Cancer Epidemiology Biomarkers & Prevention, 2008