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Study Design.

A longitudinal magnetic resonance imaging investigation of lumbar disc degeneration in asymptomatic individuals was conducted.

Objective.

To investigate risk factors for the development or deterioration of lumbar disc degeneration.

Summary of Background Data.

Numerous studies have explored the significance of certain risk factors for the development or progression of disc degeneration, but no comprehensive longitudinal magnetic resonance imaging–based study has been reported that simultaneously considers clinical, morphologic, physical, psychosocial, and occupational risk factors.

Methods.

In the 5-year follow-up evaluation of 41 asymptomatic individuals, the risk factors for the development of lumbar disc degeneration and its progression were investigated. All 41 individuals had a magnetic resonance imaging scan at baseline and at the minimum 5-year follow-up assessment using the same …