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To review the evidence from high quality human intervention studies that reported links between oat consumption and cardiovascular disease (CVD) risk factors.

Using Medline, a search was made for all randomized controlled trials published between 1990 and 2008 that met defined inclusion criteria. Studies had a minimum duration of 14 days, used oat products rather than purified extracts, and included plasma lipid levels as outcome variables.

A total of 21 eligible studies were located 13 of which reported significant reductions in total cholesterol when oats were consumed, while 14 reported significant reductions in low‐density lipoprotein cholesterol. A few studies found increases in high‐density lipoprotein cholesterol and more favourable cholesterol ratios when oats were consumed.

It was not possible to analyse …