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Differential evolution (DE) is a simple, yet very effective, population-based search technique. However, it is challenging to maintain a balance between exploration and exploitation behaviors of the DE algorithm. In this paper, we boost the population diversity while preserving simplicity by introducing a multi-population DE to solve large-scale global optimization problems. In the proposed algorithm, called mDE-bES, the population is divided into independent subgroups, each with different mutation and update strategies. A novel mutation strategy that uses information from either the best individual or a randomly selected one is used to produce quality solutions to balance exploration and exploitation. Selection of individuals for some of the tested mutation strategies utilizes fitness-based ranks of these individuals. Function evaluations are divided into epochs. At the end of each epoch, individuals between the …