Authors
Bart G Pijls, Shahab Jolani, Anique Atherley, Janna IR Dijkstra, Gregor HL Franssen, Stevie Hendriks, Evan Yi-Wen Yu, Saurabh Zalpuri, Anke Richters, Maurice P Zeegers
Publication date
2022
Source
F1000Research
Volume
11
Publisher
Faculty of 1000 Ltd
Description
Background: This review aims to investigate the association of sex with the risk of multiple COVID-19 health outcomes, ranging from infection to death.
Methods: Pubmed and Embase were searched through September 2020. We considered studies reporting sex and coronavirus disease 2019 (COVID-19) outcomes. Qualitative and quantitative data were extracted using standardised electronic data extraction forms with the assessment of Newcastle Ottawa Scale for risk of bias. Pooled trends in infection, hospitalization, severity, intensive care unit (ICU) admission and death rate were calculated separately for men and women and subsequently random-effects meta-analyses on relative risks (RR) for sex was performed.
Results: Of 10,160 titles, 229 studies comprising 10,417,452 patients were included in the analyses. Methodological quality of the included studies was high (6.9 out of 9). Men had a higher risk for …
Total citations
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