Authors
Eric J Dippel, Prakash Makam, Richard Kovach, Jon C George, Raghotham Patlola, D Christopher Metzger, Carlos Mena-Hurtado, Robert Beasley, Peter Soukas, Pedro J Colon-Hernandez, Matthew A Stark, Craig Walker, EXCITE ISR Investigators
Publication date
2015/1
Journal
JACC: Cardiovascular Interventions
Volume
8
Issue
1 Part A
Pages
92-101
Publisher
American College of Cardiology Foundation
Description
Objectives
The purpose of this study was to evaluate the safety and efficacy of excimer laser atherectomy (ELA) with adjunctive percutaneous transluminal angioplasty (PTA) versus PTA alone for treating patients with chronic peripheral artery disease with femoropopliteal bare nitinol in-stent restenosis (ISR).
Background
Femoropopliteal stenting has shown superiority to PTA for lifestyle-limiting claudication and critical limb ischemia, although treating post-stenting artery reobstruction, or ISR, remains challenging.
Methods
The multicenter, prospective, randomized, controlled EXCITE ISR (EXCImer Laser Randomized Controlled Study for Treatment of FemoropopliTEal In-Stent Restenosis) trial was conducted across 40 U.S. centers. Patients with Rutherford Class 1 to 4 and lesions of target lesion length ≥4 cm, vessel diameter 5 to 7 mm were enrolled and randomly divided into ELA + PTA and PTA groups by a 2:1 ratio …
Scholar articles
EJ Dippel, P Makam, R Kovach, JC George, R Patlola… - JACC: Cardiovascular Interventions, 2015