Authors
Anthony K Ogawa, Chris A Willoughby, Raynald Bergeron, Kenneth P Ellsworth, Wayne M Geissler, Robert W Myers, Jun Yao, Georgianna Harris, Kevin T Chapman
Publication date
2003/10/20
Journal
Bioorganic & medicinal chemistry letters
Volume
13
Issue
20
Pages
3405-3408
Publisher
Pergamon
Description
The synthesis of a series of novel dihdyropyridine diacid glycogen phosphorylase inhibitors is presented. SAR and functional assay data are discussed, along with the effect of a single inhibitor on blood glucose in a diabetic animal model.
Total citations
Scholar articles
AK Ogawa, CA Willoughby, R Bergeron, KP Ellsworth… - Bioorganic & medicinal chemistry letters, 2003