Authors
Annina S Vischer, Silvia Castelletti, Petros Syrris, Rachel Bastiaenen, Chris Miles, Deniz Akdis, Kris Denhaerynck, Daniel Jacoby, Ardan M Saguner, Andrew D Krahn, Elijah R Behr, William J McKenna, Antonios Pantazis
Publication date
2019/5/1
Journal
International journal of cardiology
Publisher
Elsevier
Description
Aims
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically determined heart muscle disorder associated with an increased risk of life-threatening arrhythmias in some patients. Risk stratification remains challenging. Therefore, we sought a non-invasive, easily applicable risk score to predict sustained ventricular arrhythmias in these patients.
Methods
Cohort of Patients who fulfilled the 2010 ARVC task force criteria were consecutively recruited. Detailed clinical data were collected at baseline and during follow up. The clinical endpoint was a composite of recurrent sustained ventricular arrhythmias and hospitalization due to ventricular arrhythmias. Multivariable logistic regression was used to develop models to predict the arrhythmic risk. A cohort including patients from other registries in UK, Canada and Switzerland was used as a validation population.
Results
One hundred and thirty-five patients …
Scholar articles
AS Vischer, S Castelletti, P Syrris, R Bastiaenen… - International journal of cardiology, 2019