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Patients with multiple sclerosis (MS) frequently experience poor gait and/or cognitive impairment, even in the early stages of the disease. As gait is often executed simultaneously with different cognitive tasks, it is essential to test gait during a cognitive load. Therefore, the main objective of this study was to assess gait and gait variations while simultaneously performing a cognitive task in patients with a clinically isolated syndrome (CIS) suggestive of MS. Fifty-two CIS patients, aged 33.8±0.2 years with an Expanded Disability Status Scale (EDSS) score of 1.7±0.2 were included in the study. The control group consisted of 28 age- and gender-matched healthy subjects. Major spatio-temporal parameters were collected via an electronic walkway (GAITRite electronic walkway system). Participants were instructed to walk under three different conditions: normal, fast, and at a normal pace while performing the modified …