Authors
Raphael D Isokpehi, Ousman Mahmud, Andreas N Mbah, Shaneka S Simmons, Lívia Avelar, Rajendram V Rajnarayanan, Udensi K Udensi, Wellington K Ayensu, Hari H Cohly, Shyretha D Brown, Centdrika R Dates, Sonya D Hentz, Shawntae J Hughes, Dominique R Smith-McInnis, Carvey O Patterson, Jennifer N Sims, Kelisha T Turner, Baraka S Williams, Matilda O Johnson, Taiwo Adubi, Judith V Mbuh, Chiaka I Anumudu, Grace O Adeoye, Bolaji N Thomas, Oyekanmi Nashiru, Guilherme Oliveira
Publication date
2011/1
Journal
Gene regulation and systems biology
Volume
5
Pages
GRSB. S7491
Publisher
Sage Publications
Description
The draft nuclear genome sequence of the snail-transmitted, dimorphic, parasitic, platyhelminth Schistosoma mansoni revealed eight genes encoding proteins that contain the Universal Stress Protein (USP) domain. Schistosoma mansoni is a causative agent of human schistosomiasis, a severe and debilitating Neglected Tropical Disease (NTD) of poverty, which is endemic in at least 76 countries. The availability of the genome sequences of Schistosoma species presents opportunities for bioinformatics and genomics analyses of associated gene families that could be targets for understanding schistosomiasis ecology, intervention, prevention and control. Proteins with the USP domain are known to provide bacteria, archaea, fungi, protists and plants with the ability to respond to diverse environmental stresses. In this research investigation, the functional annotations of the USP genes and predicted nucleotide and …
Scholar articles
RD Isokpehi, O Mahmud, AN Mbah, SS Simmons… - Gene regulation and systems biology, 2011
TA Ewemoje, AO Raji - 2011