Authors
Udensi K Udensi, Alan J Tackett, Stephanie Byrum, Nathan L Avaritt, Deepanwita Sengupta, Linley W Moreland, Paul B Tchounwou, Raphael D Isokpehi
Publication date
2014/7/1
Journal
Journal of proteomics & bioinformatics
Volume
7
Issue
7
Pages
166
Publisher
NIH Public Access
Description
Method
The altered abundance of proteins from HaCaT human keratinocyte cell line exposed to arsenic was quantified using a label-free LC-MS/MS mass spectrometry workflow. Selected proteomics results were validated using western blot and RT-PCR. A functional annotation analytics strategy that included visual analytical integration of heterogeneous data sets was developed to elucidate functional categories. The annotations integrated were mainly tissue localization, biological process and gene family.
Scholar articles
UK Udensi, AJ Tackett, S Byrum, NL Avaritt… - Journal of proteomics & bioinformatics, 2014