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Acute leukemia is one of the most common malignant neoplasms of female. Fortunately, the incidence of leukemia during pregnancy has been estimated at only 1 per 100,000 pregnancies. Since the management of acute leukemia in pregnancy consists of the challenge of optimizing chances for prolonged remission and cure in the mother while minimizing the toxicity to the unborn fetus, so there are many therapeutic and ethical dilemmas. Causing thrombocytopenia and anemia, neutropenia, leukemia can be an obstacle to the adequate obstetric management. The management of this subset of pregnant patients requires a team approach including patient, family, obstetrician and hematologist-oncologist. We experienced a case of the pregnancy with acute myelogenous leukemia at 32 gestational weeks. With induction of labor, she was delivered of a 2,250 g, healthy male baby at 34 gestational weeks. After delivery of infant, she underwent combination chemotherapy. We present this case with review of related literatures.