Authors
Christopher Phillips, W Parson, B Lundsberg, C Santos, A Freire-Aradas, M Torres, M Eduardoff, C Børsting, P Johansen, M Fondevila, N Morling, P Schneider, A Carracedo, MV Lareu, EUROFORGEN-NoE Consortium
Publication date
2014/7/1
Journal
Forensic Science International: Genetics
Volume
11
Pages
13-25
Publisher
Elsevier
Description
Emerging next-generation sequencing technologies will enable DNA analyses to add pigmentation predictive and ancestry informative (AIM) SNPs to the range of markers detectable from a single PCR test. This prompted us to re-appraise current forensic and genomics AIM-SNPs and from the best sets, to identify the most divergent markers for a five population group differentiation of Africans, Europeans, East Asians, Native Americans and Oceanians by using our own online genome variation browsers. We prioritized careful balancing of population differentiation across the five group comparisons in order to minimize bias when estimating co-ancestry proportions in individuals with admixed ancestries. The differentiation of European from Middle East or South Asian ancestries was not chosen as a characteristic in order to concentrate on introducing Oceanian differentiation for the first time in a forensic AIM set. We …
Total citations
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Scholar articles
C Phillips, W Parson, B Lundsberg, C Santos… - Forensic Science International: Genetics, 2014