Authors
Bryce B Reeve, Sandra A Mitchell, Amylou C Dueck, Ethan Basch, David Cella, Carolyn Miller Reilly, Lori M Minasian, Andrea M Denicoff, Ann M O’Mara, Michael J Fisch, Cynthia Chauhan, Neil K Aaronson, Corneel Coens, Deborah Watkins Bruner
Publication date
2014/7/8
Source
JNCI: Journal of the National Cancer Institute
Volume
106
Issue
7
Pages
dju129
Publisher
Oxford University Press
Description
Background
The National Cancer Institute’s Symptom Management and Health-Related Quality of Life Steering Committee held a clinical trials planning meeting (September 2011) to identify a core symptom set to be assessed across oncology trials for the purposes of better understanding treatment efficacy and toxicity and to facilitate cross-study comparisons. We report the results of an evidence-synthesis and consensus-building effort that culminated in recommendations for core symptoms to be measured in adult cancer clinical trials that include a patient-reported outcome (PRO).
Methods
We used a data-driven, consensus-building process. A panel of experts, including patient representatives, conducted a systematic review of the literature (2001–2011) and analyzed six large datasets. Results were reviewed at a multistakeholder meeting, and a final set was derived …
Scholar articles
BB Reeve, SA Mitchell, AC Dueck, E Basch, D Cella… - JNCI: Journal of the National Cancer Institute, 2014