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Indicates some of the ways one might try to build a modern, integrated neuroscience of personality. The authors note that the chapter will not be a comprehensive review of recent neuroscientific findings and theories concerning a range of major personality dimensions. Instead, they will illustrate the use of neuroscience to understand personality better by concentrating largely on the major cluster of personality traits that can be referred to as impulsive sensation seeking (ISS). A neurobiological model of these traits is proposed that relates them to variations in dopaminergic transmission that play a role in behavioral activation and inhibition systems.(PsycINFO Database Record (c) 2016 APA, all rights reserved)