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Methods

Four teams are currently participating in the preprocessing initiative, each one using different toolsets and preprocessing strategies (fig. 1). Preprocessed data, derivatives, and quality control metrics are made openly available for download through the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC)[6]. The ADHD-200 release included two fMRI preprocessing pipelines as well as maps of grey matter density for voxel-based morphometry (fig. 1). The Beijing diffusion imaging release includes DTI scalars along with voxel specific diffusion distributions for performing probabilistic tractography. Figure 2 illustrates various derivatives generated through these initiatives. The future ABIDE preprocessing initiative will incorporate three functional preprocessing piplines and cortical measures (fig. 3). The analytical procedures employed in the preprocessing are extensively documented on the NITRC website [2].