Yazarlar
Mehmet Kanbay, Adem Ozkara, Yusuf Selcoki, Bunyamin Isik, Faruk Turgut, Nuket Bavbek, Ebru Uz, Ali Akcay, Ramazan Yigitoglu, Adrian Covic
Yayın tarihi
2007/12
Dergi
International urology and nephrology
Cilt
39
Sayfalar
1227-1233
Yayıncı
Springer Netherlands
Açıklama
Background
Hyperuricemia has been associated with the development of hypertension, cardiovascular, and renal disease. However, there is no data about the effect of lowering uric acid level on hypertension, renal function, and proteinuria in patients with glomerular filtration rate (GFR) >60 ml/min. We therefore conducted a prospective study to investigate the benefits of allopurinol treatment in hyperuricemic patients with normal renal function.
Materials and methods
Forty-eight hyperuricemic and 21 normouricemic patients were included in the study. Hyperuricemic patients received 300 mg/day allopurinol for three months. All patients’ serum creatinine level, 24-h urine protein level, glomerular filtration rate, and blood pressure levels were measured at baseline and after three months of treatment.
Results
A total of 59 …
Toplam alıntı sayısı
Google Akademik makaleleri
M Kanbay, A Ozkara, Y Selcoki, B Isik, F Turgut… - International urology and nephrology, 2007