Authors
Stijn E Verleden, Arno Vanstapel, Joseph Jacob, Tinne Goos, Jeroen Hendriks, Laurens J Ceulemans, Dirk E Van Raemdonck, Laurens De Sadeleer, Robin Vos, Johanna M Kwakkel-van Erp, Arne P Neyrinck, Geert M Verleden, Matthieu N Boone, Wim Janssens, Els Wauters, Birgit Weynand, Danny D Jonigk, Johny Verschakelen, Wim A Wuyts
Publication date
2022/12/20
Journal
Radiology
Volume
307
Issue
1
Pages
e221145
Publisher
Radiological Society of North America
Description
Background
Interstitial lung abnormalities (ILAs) reflect imaging features on lung CT scans that are compatible with (early) interstitial lung disease. Despite accumulating evidence regarding the incidence, risk factors, and prognosis of ILAs, the histopathologic correlates of ILAs remain elusive.
Purpose
To determine the correlation between radiologic and histopathologic findings in CT-defined ILAs in human lung explants.
Materials and Methods
Explanted lungs or lobes from participants with radiologically documented ILAs were prospectively collected from 2010 to 2021. These specimens were air-inflated, frozen, and scanned with CT and micro-CT (spatial …
Total citations
Scholar articles
SE Verleden, A Vanstapel, J Jacob, T Goos, J Hendriks… - Radiology, 2022