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Purpose

In different allo-organ transplantations such as heart and kidney transplantation, feminine donor organs are associated with a significant decreased long-term survival outcome. The aim of our study was to determine if gender mismatches influence survival outcomes.

Methods

In this retrospective, single center study of 375 adult lung transplant recipients (median follow-up of 1417 days), we analyzed long-term survival and the effect of gender mismatches between recipient and donor (Kaplan-Meier, multivariate regression).

Results

More females (51.5%) were transplanted (median age 50 years; range 16-65) compared to men (median age 51 years; range 17-65; p= ns). Matched gender transplants showed a better long term survival outcome compared to mismatched gender transplants in our 16 years of follow up (43% vs 31%, p= 0.006). A gender mismatched female donor transplanted into a male showed a …