Authors
Abdulaziz Alsharifi, Georgios Kaltsakas, Martino F Pengo, Gianfranco Parati, Miquel Serna-Pascual, Gerrard Rafferty, Joerg Steier
Publication date
2023/10/1
Source
BMJ Open Respiratory Research
Volume
10
Issue
Suppl 1
Publisher
Archives of Disease in childhood
Description
Background
Electrical stimulation has recently been introduced to treat patients with Obstructive sleep apnoea (OSA). There are, however, few data on the effects of transcutaneous submental electrical stimulation (TES) on the cardiovascular system. We studied the effect of TES on cardiorespiratory variables in healthy volunteers during head-down-tilt (HDT) induced baroreceptor loading.
Method
Cardiorespiratory parameters (blood pressure, heart rate, minute ventilation, oxygen saturation, and end-tidal CO2/O2 concentration) were recorded seated, supine, and during HDT (50°) under normoxic, hypercapnic (FiCO2 5%) and poikilocapnic hypoxic (FiO2 12%) conditions. Blood pressure (BP) was measured non-invasively and continuously (Finapres). TES was individually titrated to skin sensation and gentle stimulation. We studied all participants twice on different days, once without and once with TES.1
Results
We …