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Dermal exposure data for mycotoxins are very scarce and fragmentary, despite their widespread skin contact and hazard toxicity. In this study, the transdermal kinetics of aflatoxin B1 (AFB1), ochratoxin A (OTA), fumonisin B1 (FB1), citrinin (CIT), zearalenone (ZEA) and T-2 toxin (T-2) were quantitatively evaluated, using human skin in an in vitro Franz diffusion cell set-up. All mycotoxins penetrated through the skin, except for FB1, which showed concentrations in the receptor fluid below the LoD, resulting in a K_p<3.24×10⁻⁶cm/h. OTA showed the highest permeation (K_p=8.20×10⁻⁴cm/h), followed by CIT (K_p=4.67×10⁻⁴cm/h). AFB1 and ZEA showed lower permeability rates (K_p=2.11 and 2.33×10⁻⁴cm/h, respectively). T-2 was found to have the lowest permeability (K_p=6.07×10⁻⁵cm/h). From literature-based mycotoxin-concentrations, dermal contact surface, exposure time and apparent K_p's obtained in this study, the …